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So many years into the digital revolution, even those with presumably the highest levels of computer savvy seem to get caught up by the "digital trail" — that wide wake we tend to leave as we transact an electronically mediated life.
Even a savvy digital native like Nev Schulman, star of the documentary "Catfish" (which has since been adapted into an MTV series), expresses misgivings about his own digitally mediated life.
Few others can understand the mediated life we live.
I felt a twinge of recognition when I realized that a company that was once a core part of my mediated life was getting shoved to the side.
If that happens, your children will miss out on so much good stuff that makes unmediated life far better and more interesting than a mediated life could possibly offer.
We next determined the processes that mediated life span extension by rapamycin.
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Since both the parents and the developing young need carotenoids, it has been suggested that carotenoid availability can also mediate life history trade-offs [5], [15], [16].
Carotenoid-dependent colours can thus signal individual quality and carotenoids have also been suggested to mediate life-history trade-offs.
Microbial superantigens are among the most potent antigens known, can mediate life-threatening toxic shock syndrome, and activate ∼−−20% of total T-cells among infected individuals [48].
The potential role of oxidative stress in mediating life-history trade-offs strongly prompts for an extension of these studies to the longitudinal links between individual redox status and a major determinant of fitness such as long-term survival.
Our findings imply that the impact of metformin on worm lifespan reflects the sum of indirect, E. coli-mediated life-extending effects and direct life-shortening effects.
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