Sentence examples for mediated its effect from inspiring English sources

Other inhibitory factors such as differential alteration of nerve conduction velocities mediated its effect via gate control mechanism, might have played a part in the process leading to the pain and symptoms termination.

However, the mechanisms or whether Wnt5A mediated its effect through CaMKII activation, were not investigated.

Plk1 mediated its effect on Cdh1, at least in part, through direct phosphorylation of the human phosphatase Cdc14A, controlling the phosphorylation state of Cdh1.

An additional challenge with interpreting these findings lies with understanding which component of the intervention programme mediated its effect.

Collectively, these data suggested that IFNB1 mediated its effect on autophagy, at least partly, by inhibiting the MTORC1 pathway.

Therefore, JMJD6 did not confer unresponsiveness to this growth factor, but probably mediated its effect via repression of gene expression.

Metformin mediated its effects through activation of AMPKThr172 together with inhibition of the IR/IGF-IR signalling pathway.

Thus, it is possible that glucose mediates its effect on PDE3B via a cAMP-dependent mechanism [38].

TGF-beta1, an anti-inflammatory cytokine, is upregulated following LPS stimulation, mediating its effect through SMAD family proteins.

IFNγ mediates its effect on cells by interacting with type II IFN receptors (IFNGR1 and IFNGR2).

The small GTPase Rnd1 was shown to bind to FLRT3 and to mediate its effect on cell adhesion [4].