Sentence examples for mediated inflammatory pathways from inspiring English sources
This increased risk of depression may be due in part to the adverse or toxic effects of sedative-hypnotic drugs including alcohol on neurochemistry, such as decreased levels of serotonin and norepinephrine, or activation of immune mediated inflammatory pathways in the brain.
The significant interaction between depression and IL-17 concentrations predicting MMSE scores suggests that depression may confer neural vulnerability to IL-17 mediated inflammatory pathways.
Ruscogenin has also been documented to reduce cerebral ischemic injury via NF- κB mediated inflammatory pathway in the mouse model of experimental stroke.
These findings indicate that estrogen and selective estrogen receptor modulators can influence glial-mediated inflammatory pathways and possibly protect against age- and disease-related neuropathology.
In asthma, increased FeNO reflects eosinophilic-mediated inflammatory pathways moderately well in central and/or peripheral airway sites and implies increased inhaled and systemic corticosteroid responsiveness.
This phenomenon is likely explained by the complex pathogenic process of inflammation and innate immunity in the development of gout since the MSU crystal-mediated inflammatory pathways have been reported to associate with many immunological processes (Behrens et al., 2008).
The strong association between dysregulation of TLR signaling and the development of chronic inflammatory diseases [20] highlights the need for novel strategies to identify molecular targets that modulate TLR-mediated inflammatory pathways.
Therefore, the inhibition of MMP-9-mediated inflammatory pathways may provide therapeutic strategies to brain inflammation and neurodegenerative diseases.
Vitamin E may also inhibit profibrotic activity [ 43, 44] and downregulates nuclear factor (NF -κB-mediated iNF -κB-mediatedhways iNF -κB-mediated5].
These compounds appear to be selective for NOD-mediated inflammatory pathways, inasmuch as they are ineffective at inhibiting NF-κB activation induced by TLR2, TLR4 or TNF receptors.
PXR has also been described to inhibit inflammation by strongly inhibiting NF-kB-mediated inflammatory pathways while CAR does not possess any well-reported role in inflammation (42).
