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Asthma is described as Th2 mediated inflammation of the airway [ 22, 23].
However, allergen-induced miR-21 independently mediated inflammation of IL-13Ra 1 and Stat6.
EAE progression is mainly driven by Th17 mediated inflammation of the CNS leading to the destruction of myelin, with antigen presenting cells (APC) playing a key role in the amplification of inflammation [ 37].
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These results define a new mechanism through which oxidant stress downregulates acute immune-mediated inflammation of the joints.
Coeliac disease (CD) is a chronic immune-mediated inflammation of the small intestine caused by a permanent state of intolerance to ingested gluten proteins affecting genetically susceptible individuals.
Deficient complement-mediated IC handling increases the risk of extra-hepatic IC deposition and subsequent complement-mediated inflammation of the affected tissues [ 45].
Allergic rhinitis is one of the most common allergic diseases in the world that is defined as an allergen-induced, IgE-mediated inflammation of nasal mucosa.
Allergic rhinitis is an IgE-mediated inflammation of the upper airway that causes naso-ocular congestion, pruritis, rhinorrhea, and sneezing [ 1].
Rheumatoid arthritis (RA) is a chronic autoimmune disease with 1% prevalence in the industrialized countries, characterized by cytokine-mediated inflammation of the synovial lining of the diarthrodial joints and the destruction of cartilage and bone [ 1].
Hypersensitivity pneumonitis (HP) is a complex syndrome of variable intensity and clinical history, caused by an immune-mediated inflammation of the lung parenchyma due to the continued inhalation of a wide range of antigens [ 1].
The model replicates many of the features of human disease, with C. difficile toxin-mediated inflammation of the gastrointestinal (GI) tract resulting in histopathological changes in the tissue comparable to those observed in humans (11).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com