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While initial quick signalling is mediated generally through specialized sensory molecules or complexes, it is then followed by transcription regulatory events that lead to a prolonged reorganization of cellular status [ 39].
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Androgens play key roles in vertebrate sex differentiation, gonadal maturation and reproductive behaviour and their actions are generally mediated through specific nuclear receptors.
Accordingly, 'acid handling' by the kidney is generally mediated through Cl- balance.
But the expression of God's will was almost always mediated through other people's (generally older white men's) lens and words.
"The L.A. we experience is mostly mediated through windshields and cellphones," Mr. Burns said.
Hormone stimulation of tumour growth is generally associated with oestrogen, whose action is mediated primarily through the ER.
The action of purines and pyrimidines is mediated through an extended family of purinoceptors, generally divided into P1 adenosine receptors and P2 receptors for ATP and related nucleotides.
Generally, platelet aggregation and activation are mainly mediated through adhesion of platelets to the site of injury, and through the action of endogenous agonists such as collagen, ADP, and thrombin, followed by the release of TXA2 and serotonin, which act as amplification factors in platelet aggregation [ 25, 26].
Progression through this cascade is generally mediated by a sequence of extracellular signals, initiated by the differentiating cells themselves or by their environment.
The conventional view is that evolutionary change is generally mediated by a favorable mutation in a gene that then washes through the whole population, a process called a hard sweep because all other versions of the gene are brushed away.
Apoptotic cell death signaling is generally mediated by two distinct pathways that are connected in a unique loop structure through the final downstream activation of caspase-3 molecules [13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com