Sentence examples for mediated fusion with from inspiring English sources

These vesicles are then competent to undergo Ca2+ mediated fusion with the plasma membrane, in response to neuronal stimulation.

Recent studies have shown that θ-defensins are able to interact with viral gp41 to prevent HIV-1 env mediated fusion with the cytoplasmic membrane by blocking the formation of the six-helix bundle required for viral fusion [30], [31].

SPL7013 inhibited both X4 and R5 envelope mediated fusion with 50% fusion concentrations (FC50 ± standard error) of 0.08±0.02 µM (n = 3) and 0.94±0.19 µM (n = 4), respectively (Figure 4C).

The fusion inhibitor T-20 (enfurvitide) was included as a positive control and inhibited both X4 and R5 mediated fusion with FC50 values of 2.0±0.3 nM and 4±1 nM, respectively while the NNRTI, efavirenz did not inhibit cell-to-cell fusion (Figure S3).

As described by Jones et al., there is significant evidence that this series inhibits glycoprotein-B mediated fusion with the host cell membrane.

We treated ES cells with 3 μM MEK inhibitor for 3 days prior to polyethylene glycol (PEG) mediated fusion with brain-derived neural stem (NS) cells.

Both extruded and non-extruded CXCR4-proteoliposomes participated in PEG-mediated fusion with 293T cells (Figure S3).

SIL was as efficient as silymarin at inhibiting HCV-mediated fusion, with IC50 of ca. 6 µM and 5 µM respectively (see also [11]).

Future studies will examine HA-mediated fusion with target membranes that more closely mimic the complex conditions found in endosomes.

Ensemble proteoliposome fusion experiments showed that Munc18 binds preassembled SNARE complexes, and effectively promotes SNARE-mediated fusion with full-length syntaxin (11).

Another interesting example of entry inhibitors is a thiourea derivative that is reported to block HCMV glycoprotein B-mediated fusion with host cells.