Sentence examples for mediated firm adhesion from inspiring English sources

We have shown previously that CXCR4 signaling promotes retention of B-cell precursors in the BM [30], presumably through VCAM-1/VLA-4 mediated firm adhesion [31], [32] and lack of CXCR4 leads to the release of these precursors into the periphery.

SIRPα overexpression reduced β2 integrin-mediated firm adhesion of THP-1 cells to either TNFα stimulated HMEC-1 monolayers or to immobilized intercellular adhesion molecule-1 (ICAM-1).

Monocytes express CC chemokine receptor 2 (CCR2), which binds monocyte chemoattractant protein-1 (MCP-1), leading to β2 integrin-mediated firm adhesion and subsequent transmigration of adhered monocytes through the vascular endothelium [8].

These steps include selectin-mediated rolling of leukocytes as well as integrin-mediated firm adhesion and transplatelet migration.

Activated intergins display an increased affinity and avidity, which is prerequisite for integrin-mediated firm adhesion of immune cells to the vascular endothelium.

After injury ICAM-1 interacts with leukocyte integrins to mediate firm adhesion of activated neutrophils to endothelium and diapedesis [ 4– 7].

The αMβ2 (Mac-1) integrin mediates firm adhesion of leukocytes to inflamed vessels by interacting with its endothelial cell counter-receptor intercellular adhesion molecule-1.

The capacity of p85β to enlarge the number of centrally localized larger cell adhesions concurs with p85β enhancement of cell adhesion, as centrally localized adhesions mediate firm adhesion (Wolfenson et al., 2013).

Initial leukocyte rolling is selectin-mediated while firm adhesion is mediated by integrin binding to ICAM-1 and VCAM-1, with the latter more important in initiation of atherosclerosis.

This prolonged contact with the endothelium may be necessary to promote leukocyte activation and trigger integrin-mediated arrest and firm adhesion.

This results in firm adhesion, mediated by the family of adhesion molecules called integrins.