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Thus the effect of reduced DaPKC activity on ept tumor growth could be mediated exclusively through effects on Notch and Crb.
Together, these data strongly demonstrate that CRF induced CREB phosphorylation in striatal neurons is mediated exclusively through CRFR1, with CRFR2 playing no discernable role.10.1371/journal.pone.0018114.g002Figure 2 CRFR1 mediates CRF-induced CREB phosphorylation.
Nuclear export of this protein is mediated exclusively through CRM1 (Stommel et al, 1999).
Indeed, strychnine toxicity is mediated exclusively through GlyRs, death being caused by arrest of breathing musculature.
Thus, we cannot know that the inhibitory effect of atosiban on the gastric emptying is mediated exclusively through oxytocin receptors.
It was reported that the neuroprotective action of arundic acid was mediated exclusively through the modulation of astrocytic function.
Similar(50)
Importantly, the CTH1 mediated reduction of IFU was found to be mediated exclusively by CD4+ T cells.
Interestingly, recognition of the P1.4 epitope peptide is mediated almost exclusively through the complementarity-determining regions of the heavy chain.
We therefore stimulated total MLN cells isolated from neonates and adults with CL075, which mediates stimulation preferentially through TLR8, or with CL087, which mediates stimulation exclusively through TLR7, to identify the TLR used in small ruminant species more precisely.
In TMFs, JFF spin−spin coupling values are only observed between CF3 groups sharing the same hexagon or pentagon, because the coupling is almost exclusively mediated by through-space Fermi-contact overlap of F atom lone pairs (see refs (4), (32), (50), and references therein).
However, it remains unclear if the repressive effects of S303 phosphorylation on HSF1 activity are exclusively mediated through K298 sumoylation or occur through additional mechanisms.
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