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Without MORC-1 and nuclear RNAi, MET-1-mediated encroachment of euchromatin leads to detrimental decondensation of germline chromatin and germline mortality.
However, it has been shown that NELF-mediated Pol II pausing can prevent the encroachment of nucleosomes at the promoter-proximal region, suggesting that NELF may support multiple rounds of transcription in vivo by maintaining a nucleosome-free region at the promoter (Gilchrist et al., 2010; Sun and Li, 2010).
These observations in toto suggest that a heritable epigenetic template generated by transcription-dependent H3K36 methylation in adult germ cells, which can persist in gamete chromatin and is maintained in the zygote by MES-4 activity, helps prevent encroachment of a repressive chromatin by PRC2-mediated H3K27 methylation in the offspring.
"There is always encroachment of the rules," Colonel Mitra said.
Stallman was uneasy over the increasing encroachment of proprietary software.
The encroachment of the city today is unparalleled, he says.
He describes the introduction of photo radar as "another encroachment of our rights".
The worst has been observing the gradual destruction of hope and the encroachment of despair.
The patriarch has sought to unify the faithful with warnings of the encroachment of secular values.
Fewer still escape the cultural encroachment of ethnic Han entrepreneurs and the market economy.
Like all Egyptian politicians he bows to the encroachment of religion in public life.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com