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Palumbo, J. S. et al. Platelets and fibrin ogen) increase metastatic potential by impeding natural killer cell – mediated elimination of tumor cells.
Such immunosuppressive effects by mycolactone would prevent an immune system mediated elimination of bacteria from infected tissue.
Taken together, these results suggested that GST genes play important roles in ThbZIP1 mediated elimination of cellular ROS generated by salt stress.
An additional pH-dependent mechanism of drug resistance, recently described for cisplatin, includes both extracellular sequestration and exosomes mediated elimination of the drug from melanoma cells [ 43].
The GSH depleting prodrugs described in this study could potentially have a role in inhibiting the glutathione-S-transferase mediated elimination of some chemotherapeutic drugs.
Among several strategies, Cre /lox P induced site- specific recombination strategy observed in bacteriophage P1 has been widely used for recombination mediated elimination of the SMGs [ 30, 31, 33- 37].
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Cockburn, I. A. et al. In vivo imaging of CD8+ T cell-mediated elimination of malaria liver stages.
We hypothesized that anti-CD47 antibody-mediated elimination of circulating tumor cells occurred through phagocytosis, a previously described mechanism for blocking anti-CD47 antibodies.
Similarly, the target-mediated elimination of antibodies by internalizing, membrane bound antigens (receptors) can be decreased using novel engineering approaches.
To identify the molecular mechanisms involved in YAP-mediated elimination of injured hepatocytes, we analysed gene expression profiles in livers of mice expressing YAP (WT), YAP (1SA), YAP (2SA), YAP (5SA) or YAP (5SA/TEAD*) via HTVi.
How protein disaggregation is achieved and whether survival is solely dependent on ClpB-mediated elimination of aggregates or also on reactivation of aggregated proteins has been unclear.
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