Sentence examples for mediated disruption of from inspiring English sources

Considering that CRISPR/CAS9 gene editing technology could induce off-target genomic mutations, the Jurkat-KI-R5 cells can be further employed to improve the efficiency and safety of CRISPR/Cas9 mediated disruption of the CCR5 gene.

Thus, RKIP appears to transiently protect cells from locostatin mediated disruption of the actin cytoskeleton.

Because OHCs and astroglial cultures are cultivated in different culture media we elucidated whether or not the Aβ mediated disruption of MTT reduction is influenced by the culture medium.

It is based on EE-mediated disruption of intercellular adhesion in confluent endothelial cell cultures.

These findings are the first to demonstrate a targeted nuclease-mediated disruption of HBV cccDNA.

Interestingly, in Nicotiana benthamiana cells, overexpression of ERD10 conferred resistance to latrunculin-mediated disruption of actin filaments.

Our work demonstrates that TGF-β tumor suppression functions through an EMT-mediated disruption of a lineage-specific transcriptional network.

Colchicine-mediated disruption of MT lead to total inhibition of the response to the thigmic stimulus in tendrils of Pisum and to a reduced response in Bryonia.

Therefore, it is likely that the caspase-mediated disruption of respiratory chain complex I and II function contributes to high ROS production during apoptosis.

Inducible shRNA knockdown and Cas9-mediated disruption of the LAMA5 gene dramatically reduced hPSC self-renewal and increased apoptosis without affecting the expression of pluripotency markers.

Antibody-mediated disruption of the annexin A5 anticoagulant shield has been posited to be a thrombogenic mechanism in the antiphospholipid syndrome.