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Peretz, A. et al. Flow mediated dilation of the brachial artery: an investigation of methods requiring further standardization.
Flow mediated dilation of the brachial artery is impaired with endothelial dysfunction.
For example, a recent study in Boston examined endothelial function in diabetics, as assayed using flow mediated dilation of the brachial artery (O'Neill et al. 2005).
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These results indicate that estrogens do not decrease eNOS expression or diminish NO-mediated dilation of bone medullary arterioles.
E preserves the normal endothelium-mediated dilation of coronary arteries, and P does not reverse this potential cardioprotective mechanism.
With more direct relevance for headaches and migraine, we tested whether this would also affect CGRP-mediated dilation of meningeal arteries, which we subsequently assessed in rats.
Secondary outcomes included pulse wave velocity, flow-mediated dilation of the brachial artery, baroreflex sensitivity, and left ventricular mass.Clinic-measured BP was reduced by 16.1/9.9 mm Hg (DASH plus weight management); 11.2/7.5 mm (DASH alone); and 3.4/3.8 mm (usual diet controls) (P <.001).
FMD, flow-mediated dilation of the brachial artery; NMD, nitrate-mediated dilation of the brachial artery; PWV, carotid-femoral pulse wave velocity.
FMD, flow-mediated dilation of the brachial artery; HbA1c, glycated hemoglobin; HDL-c, high density lipoprotein cholesterol; LDL-c, low density lipoprotein cholesterol; NMD, nitrate-mediated dilation of the brachial artery; PWV, carotid-femoral pulse wave velocity.
Polygraphy was recorded during study nights, endothelial function (flow-mediated dilation of the brachial artery), questionnaires and blood sampling were performed on the morning after each study night.
In a recent study O'Neill et al. (2005) reported that PM was associated with flow-mediated dilation of the brachial arteries.
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