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A skin biopsy revealed an intense lymphocytic infiltrate and immune mediated destruction of nevomelanocytes (data not shown) consistent with our previous description of T cell mediated vitiligo[18].
The underlying pathophysiology is thought to be an aberrant immune response involving the T-cell mediated destruction of hematopoietic stem cells.
Some authors have noted residual gliosis in the perifornical region [13], which combined with the strong HLA association, favors the hypothesis of autoimmune mediated destruction of HCRT neurons.
RNase H+ mediated destruction of template RNA can prevent this problem and improve the sensitivity of qPCR analysis.
Details about the Auxin mediated destruction of AID tagged proteins in yeast was previously described (Eng et al., 2014).
Gene transfer experiments demonstrate that TIMP-1 specifically inhibits the synovial fibroblast mediated destruction of cartilage in the SCID mouse model.
Similar(54)
T cell-mediated destruction of the myelin sheath causes inflammatory damage of the CNS in multiple sclerosis (MS).
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of pancreatic beta cells leading to inadequate glycemic control.
This study was designed to evaluate gene regulation caused by US-mediated destruction of microbubbles in the heart.
Type 1 diabetes (T1D) is an autoimmune disorder characterised by the immune-mediated destruction of insulin-producing pancreatic beta cells.
Type I diabetes (TID) is an autoimmune disease characterized by a T cell-mediated destruction of insulin-producing β cells.
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