Sentence examples for mediated depression of from inspiring English sources

Thus, we show that the depression of ANP on ICaL is through the particulate GC, cGMP and PDE2 mediated depression of cAMP-PKA.

Taken together, these results indicate that ANP induced depression of action potentials and ICaL is due to activation of particulate guanylyl cyclase (GC), cGMP production and cGMP-activation of PDE2 mediated depression of adenosine 3', 5' cyclic monophophate (cAMP cAMP-dependent protein kinase (PKA) in early cAMP cAMP-dependent

Histamine H3 receptor-mediated depression of synaptic transmission in the dentate gyrus of the rat in vitro.

The adenosine A1 receptor-mediated depression of the fEPSP was more strongly correlated with changes in HBF and oxygen delivery than with arterial PO2.

In addition, a significant impairment of mGlu II-mediated depression of field excitatory postsynaptic potentials at mossy fiber-CA3 synapses was detected in chronically epileptic rats.

The present study was designed to investigate the relative contributions of arterial PO2, local cerebral blood flow, and oxygen delivery to the adenosine A1 receptor-mediated depression of evoked synaptic transmission recorded in the rat hippocampus.

Ampakines counteract μ-opioid receptor-mediated depression of XII motoneuron inspiratory activity.

The μ-opioid receptor-mediated depression of XII MN inspiratory output is hypothesized to involve ACh release and the subsequent presynaptic inhibition of glutamatergic transmission through activation of muscarinic receptors [24], however, this finding is controversial [2].

An involvement of PKG in the ANP-mediated depression of ICaL was excluded for ES cell-derived cardiomyocytes since in the presence of KT5823, a PKG selective inhibitor, ANP still inhibited the ICaL (Fig. 7A), and clamping of cAMP-PKA levels abolished ICaL depression.

Studies thus suggest that NO-mediated depression of myocardial contractility appears in two separate time frames by two distinct pathways.

Thus, endotoxin-mediated depression of inflammatory immune responses may contribute to decreased ability of malaria patients to control secondary bacterial infection.