Sentence examples for mediated depending on from inspiring English sources

Further studies using the kinase inhibitor H89 demonstrated that the nucleosomal response is mediated, depending on the stimulus, either via the extracellular signal – regulated kinase (ERK) or p38 MAP kinase cascades, but not the c-Jun amino-terminal kinase/stress-activated kinase (JNK/SAPK) pathway [43].

In conclusion, plumbagin induces apoptosis in colonic cancer cells through TNF-α mediated pathway depending on expression of COX-2 expression.

We suggest that the basic region is a modulator involved in regulation of the Hsf1-mediated activation depending on the architecture of its binding site.

Our data demonstrate the involvement of Rac signaling in the establishment of cadherin-mediated adhesion depending on the spatial organization of AJs.

37 Thus, it seems likely that C. kefyr affects some specific immune-mediated diseases, depending on the underlying pathology.

The epithelial cell responsiveness to cytokines is subject to effective positive and negative feedback mechanisms that could significantly alter the receptor-mediated signaling, depending on cytokine exposure.

In conjunction with IP6K, the IP kinase activity of IPMK plays a critical role in generating IP7 (Fig. 1), which is either an Akt inhibitor or a regulator of p53-mediated apoptosis, depending on cellular context.

High-risk HPVs target hScrib and hDlg for ubiquitin-mediated degradation depending on the E6AP ubiquitin-protein ligase (Nakagawa and Huibregtse, 2000) (For hDlg, unpublished data of SN and JMH).

The mechanisms of action of EGFR antibodies against A431 cells in vivo are likely to involve a combination of Fab- and Fc-mediated effects depending on the antibody concentration at the tumour site.

PGRMC1 has been demonstrated to either increase or decrease the rate of CYP-mediated metabolism, depending on the CYP substrate pair being examined, although perhaps not directly through electron transfer.

Furthermore, our experiments demonstrated that recombinant IL-1β restored joint inflammation in TLR4-/ mice, indicating that IL-1β promotes antibody-mediated joint inflammation, depending on TLR4-mediated immune responses.