Sentence examples for mediated deletion of from inspiring English sources

Cre – loxP mediated deletion of the PGK-NeoR cassette resulted in ΔHSs/ΔHSs ES cells.

We demonstrated that homozygous Cre-recombinase mediated deletion of Wwox Exon 1 lead to complete ablation of Wwox expression.

Hence, physiological consequences are expected, especially in combination with defects resulting from Cre mediated deletion of any gene under investigation.

K14-cre mediated deletion of Trsp blocked the expression of Sec tRNA in keratinocytes, in turn preventing the synthesis of selenoproteins in this cell type.

AAV-Cre mediated deletion of the VGLUT2 gene in the rPCRt, and hence glutamate release by rPCRt neurons, resulted in the near complete elimination of masseter twitches during REM sleep in mice.

Moreover, PCR genotyping of E10.5 limb bud mesenchyme showed robust and essentially equivalent Prx1-Cre mediated deletion of c-Myc and N-Myc (data not shown), indicating that any differences observed were not due to differences in ablation efficiency.

Cre-mediated deletion of β1-integrin was achieved by treating Itgβ1fx/fx CreER™ MECs with 100 nM 4OHT.

Cre-mediated deletion of exon 5 is expected to produce a frame shift of the remaining sequence and convert the floxed PiT1 allele to a null allele.

tumors (Figure 4D), indicating Cre-mediated deletion of the Bcl-x locus in the vast majority of beta cells of RIP1-Tag2 RIP-Cre; Bcl-xfl/fl tumoRIP1-Tag2 RIP-Cre

Immunoblots show an increase in NIK protein that corresponds with the Cre-mediated deletion of the STOP sequence (Fig 1D, E).

We therefore focused our studies on the immediate early effects of the first days following Cre-mediated deletion of Ring1b in the viable, adherent ES cells.