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The data do not indicate a distinct role for the SBD in driving protrusion and thus do not fully account for the p130Cas mediated cell migration response.
We examined the role of Stat3 in H-RasV12 mediated cell migration, invasion and cellular transformation using H-RasV12 transformed mammary epithelial cells (MCF10A-Ras).
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The disintegrin domain in ADAM33 can mediate integrin α9β1-dependent cell adhesion [ 4] and can inhibit α5β1 integrin-mediated cell migration [ 5].
The model accounts for EGF-mediated cell migration and cell mitosis.
Huang JS, Cho CY, Hong CC, Yan MD, Hsieh MC, Lay JD et al. Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism.
In cells from the BV-2 microglia cell line, ABHD6 knockdown reduced hydrolysis of 2-AG and increased the efficacy with which 2-AG can stimulate CB2-mediated cell migration.
(G) Validation of miR-24-mediated cell migration by scraping line method.
To this purpose, CXCL12-mediated cell migration was measured in NB cells.
BMP-mediated cell migration requires activation of the small GTPase Cdc42 and LIMK1 activities.
However, the molecular mechanism involved in AR-mediated cell migration still remains elusive.
Fifteen of these small molecules were shown to inhibit specifically CCR4-mediated cell migration, including that of CCR4+ Tregs.
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