Sentence examples for mediated cell kill from inspiring English sources
This provides further evidence that radiation and immunotherapy can lead to immune mediated cell kill in patients with established tumors who have already undergone other cancer treatment modalities.
Radiation can also increase tumor cell susceptibility to immune mediated cell kill by altering cellular surface expression of a number of molecules.
When rituximab binds to CD20 at the cell surface rituximab activates complement-dependent cytotoxicity and human Fc receptors, mediating cell killing through an antibody-dependent cellular toxicity.
MICA and MICB are important NKG2DLs which can effectively activate the NKG2D receptors and thereby induce NK cell-mediated cell kill [ 21].
Since no tumor-antibody interaction is defined in FIRM at this point (all the individual models, MK, DB or BL, lacked a mechanistic description of antibody-mediated cell kill), simulations of tumors will not include migration of tumor antigens (debris in the DB model) into the blood from the target organ.
The immune effects of NK cells are dependent on the natural killer group 2D (NKG2D -mediated cell kill, aNKG2D -mediatedcellf Nkill-mediandd cytheoxicity has befficiencytofcorrelate with the expression levels of NKG2D ligands (NKG2DLs) on the target cytotoxicity
Furthermore, the high protein synthesis rates of pancreatic cancer cells with activated Ras compared with the low protein synthesis rates of normal cells suggest that this therapeutic strategy may selectively kill pancreatic cancer cells via ER stress-mediated cell death.
Note that it is well known that NK cells are the only population within PBMCs mediating K562 cell killing.
In addition to ADCC, CDC is another mechanism by which therapeutic mAbs can mediate target cell killing.
By fixing complement or activating immune cells such as natural killer cells, macrophages, and T cells, antibodies can mediate additional cell killing against target cells.
As it returns to the ground state, there are two ways in which the energy released can mediate selective cell killing.
