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Briefly, ATG7 coordinates tumor suppressor p53-mediated cell division cycle and cell apoptosis via physical interaction with p53 under limited nutrients, providing an explanation for the simultaneous or sequential metabolic stress-induced events, including exit from cell cycle, induction of autophagy, and activation of cell death signaling.
Earlier studies based on gene expression and induction analysis implied that plant RACK1 may have a role in hormone-mediated cell division [ 5, 7], UV and salicylic acid responses [ 8].
The miRNAs mediated delayed cell division and activation of late apoptosis in MiaPaCa-2 cells.
Ubiquitin-mediated protein degradation plays a variety of roles in the regulation of many developmental processes, including mediating stem cell division through degradation of cell cycle regulators.
The authors posited that this correlation indicates a coupling of L1-mediated retrotransposition to cell division, as transcripts highly expressed during cell division would be more likely to undergo retrotransposition.
The obtained experimental data indicated that NO is required for and can stimulate auxin-mediated activation of cell division as well as embryogenic cell formation from differentiated leaf cells (protoplasts), but is not involved in the regulation of cell cycle progression of continuously dividing cells.
In addition, actin/myosin mediated cell migration ceases during cell division when cortical actin must be reorganized in order to specify where the cleavage furrow is activated during cytokinesis.
We recently demonstrated that mitochondria are inherited by an ordered microtubule-mediated mechanism in mammalian cell division.
PARD3 inactivation-mediated loss of asymmetric cell division could lead to accumulation of stem or progenitor cells and to disruption of 3D tissue organization, resulting in the initiation of tumor formation.
Wakamatsu, Y., Maynard, T.M. & Weston, J.A. Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis.
This suggests that parental nucleosomes containing H3K9 methylation may play crucial role in recovery of G9a/GLP-mediated H3K9 methylation landscape beyond the cell division in vivo.
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