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Kuroda, S. et al. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin mediated cell-cell adhesion.
Thus, our results underscore the need not only to analyze interactions of a given mAb with single FcγR on the protein level, but also to address whether the immunological microenvironment is appropriate to support FcγR mediated cell-cell interactions.
Thus E-cadh- mediated cell-cell adhesion contributes to correct cell movement and rearrangement during epiboly.
IQGAP-1 is a regulator of E-cadherin mediated cell-cell adhesion.
Treatment with DMOG markedly altered VE-cadherin mediated cell-cell adhesions.
The calcium chelating agent EGTA was used to disrupt E-cadherin mediated cell-cell adhesion in MCC.
Cadherins comprise a superfamily of transmembrane glycoproteins involved in calcium mediated cell-cell adhesion and hence, tissue integrity [ 49].
Cadherin association with catenins is necessary for strong cadherin-mediated cell-cell adhesion.
Previous studies have shown that induction of cadherin-mediated cell-cell adhesion leads to tight junction formation, and that blocking cadherin-mediated cell-cell adhesion inhibits tight junction assembly.
E-cadherin-mediated cell-cell junctions play a prominent role in maintaining the epithelial architecture.
However, the introduction of this mutation into full-length N-CAM expressed in COS-7 cells failed to affect N-CAM-mediated cell-cell adhesion.
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