Sentence examples for mediated by up from inspiring English sources

This reprogramming is mediated by up regulation of the JNK pathway and transient debilitation of the epigenetic control mechanism.

Azole resistance in Candida sp. is mediated by up regulation of genes encoding ERG11, a lanosterol demethylase, MDR1 and by CDR (Candida drug resistance) efflux pumps.

The study demonstrated a potential antidepressant-like effect of EA treatment on CUS induced depression model rats, which might be mediated by up-regulating the hippocampal progenitor cell proliferation.

Taken together, the accumulation in G0/G1 by NS-398 might be mediated by up-regulation of p21.

In conclusion, NSAIDs induce apoptosis in gastric cancer cells which may be mediated by up-regulation of c- myc proto-oncogene.

It is tempting to speculate that the mechanism of immature B cell survival and differentiation in response to T cell help is mediated by up-regulation of genes such as bcl-2 and bcl-xL.

These data suggested that down-regulation of NDRG2 could enhance sensitivity of Hela cells to cisplatin through inhibiting Bcl-2 protein expression, which might be mediated by up-regulating miR-15b and miR-16.

Recently, we developed multi-drug resistant NB in in vitro models and have demonstrated for the first time that an increased malignant phenotype in multidrug-resistant neuroblastoma cells is not mediated by up-regulated functional Pgp [ 7].

Based on the results of the present study, we suggest that the stimulatory effect of ARA extract on adipogenic differentiation may be mediated by up-regulation of PPARγ expression and activity.

Down-regulation of NDRG2 could enhance cisplatin-induced apoptosis of Hela cells through inhibiting Bcl-2 protein expression, which might be mediated by up-regulating miR-15b and miR-16.

LPS priming is mediated by up-regulation of TLR4 and downstream messengers in cells including neutrophils and macrophages (Lin et al., 2006; Hoogerwerf et al., 2010; Reino et al., 2012).