Sentence examples for mediated by structurally from inspiring English sources

Most of this transport is mediated by structurally related proteins referred to as mitochondrial carriers (MCs) (Palmieri, 2014).

The MHR of CA has been recently identified as one of three critical determinants for antiviral activity that is mediated by structurally different PF-46396 that has a similar mode of action to that of bevirimat.

These different functions are often mediated by structurally related receptors, many of which contain modular carbohydrate-recognition domains (CRDs) that fall into more than a dozen different structural families (Taylor and Drickamer 2011).

The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3, and FGFR4.

The first three pathways are mediated by two structurally related, but distinct, estrogen receptors (ERs): ER-α and ER-β.

Detailed studies comparing rat mesenteric resistance and basilar arteries demonstrated that ET-1 and ET-2 initiate and maintain vasoconstriction by different downstream mechanisms raising the prospect of 'biased signalling' mediated by two structurally different agonists activating the same receptor (Compeer et al., 2013).

Ribosomal protection is mediated by GTP-dependent proteins structurally similar to ribosomal elongation factors EF-Tu and EF-G, blocking the ribosome binding of tetracyclines such as minocycline 2 and doxycycline 1 and thereby preventing the inhibition of ribosome function, allowing protein synthesis and bacterial survival.

Tetracycline efflux is mediated by a family of structurally and mechanistically related proteins named the Tet proteins, which, as part of the major facilitator family of transport proteins, couple proton motive force to the exchange of a tetracycline-cation complex, thereby decreasing intracellular concentrations of tetracycline and allowing bacterial growth and survival.

We could recently show that interference with critical steps of platelet tethering to the vessel wall can prevent ischemic stroke in the mouse model of transient MCA occlusion (tMCAO) [6], [7].The initial tethering of platelets at sites of vascular injury is mediated by GPIb-V-IX, a structurally unique receptor complex exclusively expressed in platelets and megakaryocytes [8].

In contrast to its seemingly simple nature, membrane fusion between two different cells is mediated by a number of distinct and structurally unrelated membrane fusion-molecules.

Structurally, this interaction is mediated by binding of the α-helical BH3 region of the proapoptotic proteins to a conserved hydrophobic groove on the prosurvival proteins.