Sentence examples for mediated by side from inspiring English sources

The second type of inter-molecular interactions is mainly mediated by side chains (Fig. 4C E; Tables S2 and S3) and is observed between: 1) amino acids of αHD of HadA and the helices α1 and α2, as well as the loop connecting these helices of HadB, 2) helix α1 of HadA and HadB, 3) β2 of HadA with αHD of HadB.

Of these, five hydrogen bonding contacts were mediated by side chains.

Photoactivation disrupts and reorganizes multiple constrains mediated by side chains and bound water, which transmits signaling from the chromophore and opens a groove on the cytoplasmic surface of the receptor, finally promoting catalytic exchange of GDP to GTP in transducin α.

Interactions between the two molecules are mediated by side chain residues of the CDR loops of the sAB and the hinge region that connects the two tandem fibronectin (FN) domains of hPRL-R.

An analysis of four zinc-devoid pZBDs, from Bt-GluRS, Tt-GluRS, Mt-GluRS and Te-GluRS, showed a number of long-range H-bonds (more than four residue separation in the sequence; Supplementary Figure S6), mediated by side chains.

Except for a carbonyl-histidine hydrogen bond, the entire interaction is mediated by side-chain packing interactions and a glutamate-arginine charged interaction.

Nevertheless, in the absence of the side chain carboxylate of E90, the charge complementation of R6G appears to be assumed appreciably by dipole-charge interactions mediated by the side chain oxygen atoms of Q64 and Q96, located within 3.0 and 3.5 Å of the R6G N2 and N1 ethyl amino nitrogen atoms, respectively.

This binding is mediated by HS side chains and can be inhibited by heparin[ 26, 27].

Moreover, proper positioning of the SAM cofactor is further mediated by the side chain of M155.

This hydrogen bond is mediated by the side chain of Glu-297, but also the backbone carbonyl of Thr-295 is in very close vicinity to A-1493 with a minimum distance of 3.7 Angstroms.

This trend supports the hypothesis that high levels of steroids lead to cardiovascular disease mediated by steroid side effects such as arterial hypertension, obesity, diabetes, or hypercholesterolemia [ 23, 26– 28].