Sentence examples for mediated by receptor from inspiring English sources

In contrast, iron deficiency or exogenous hemin did not activate the reporter until after 3 h, suggesting that induction of the promoter by hemoglobin is mediated by receptor signaling rather than heme or iron flux into the cell.

Additionally, THC seems to have neuroprotective effects mediated by receptor independent mechanisms due to its antioxidant properties [17], [26].

In the blood-brain-barrier (BBB) endothelial cells, the internalization of Aβ40 was claimed to be mediated by receptor for advanced glycosylated end products (RAGE) at the luminal surface [19] and LRP1 at the abluminal surface [20].

Signals mediated by receptor tyrosine kinases (RTKs), such as stresses, growth factors, antigens, among many others, lead to the phosphorylation of hundreds of tyrosine residues leading to conformational changes that allosterically regulates interactions with specific binding partners[2], [3].

These findings indicate that the pro-obesity effects of peripherally applied NT4 are not mediated by receptor down-regulation and that peripheral NT4 administration may directly reduce metabolic rate independent of its effect on food intake in the nonhuman primates.

Instead, we suggest that the stimulatory effects of ATR on the NR5A receptor subfamily (SF-1, LRH-1, and zff1d) are likely mediated by receptor phosphorylation, amplification of cAMP and PI3K signaling, and possibly an increase in the cAMP-responsive cellular kinase SGK-1, which is known to be upregulated in infertile women.

This indicated that increased cholesteryl ester uptake was likely mediated by receptor-mediated endocytosis.

This suggests that the delivery of the vitamin D to the placenta by its binding protein may be an important determinant of vitamin D action, possibly mediated by receptor-mediated endocytosis.

Transmission mediated by these receptors is more prominent at hyperpolarizing potentials compared with transmission mediated by receptors containing other NR2-type subunits.

Biospecific cell adhesion is mediated by receptor-ligand bonds.

Agtr1A mice have also been useful in defining angiotensin responses that are mediated by receptors other than AT1A.