Sentence examples for mediated by proinflammatory from inspiring English sources

These catabolic events are largely mediated by proinflammatory cytokines and mediators, for example, matrix metalloproteinases (MMPs), and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) [ 59].

A systemic fetal inflammatory response is an independent risk factor for severe neonatal morbidity, mediated by proinflammatory cytokines.

The activation of these keratocytes is mediated by proinflammatory cytokines, such as IL-1 and IL-6 [7].

Induction of ATF3 is mediated by proinflammatory factors, such as nitric oxide and NF-κB.

NF-κB appears to be a common target of multiple converging catabolic signaling pathways mediated by proinflammatory cytokines.

In studies examining rheumatoid arthritis synovial cells and osteoarthritis chondrocytes, treatment with dexamethasone decreased mPGES-1 mRNA and protein expression mediated by proinflammatory cytokines [ 23, 25, 27].

To determine whether the protective effect of melatonin in testicular ischemia/reperfusion (IR) injury is mediated by the proinflammatory molecules.

It is known that the primary host immune response is mediated by the proinflammatory cytokines IL-1β, IL-6, and TNFα [42].

This phenomenon is not mediated by the proinflammatory cytokines, which are known to stimulate CRP production in hepatocytes and induce RANKL expression in RA.

Since potent stimulatory factors such as IL-6 and IL-8 are induced by adiponectin soon after stimulation with this factor, the effects observed with adiponectin may be mediated by these proinflammatory cytokines.

The relationship of vitamin D deficiency to large vessel stroke and other atherosclerotic cardiovascular diseases may be mediated by atherogenic proinflammatory cytokines that foster atherosclerotic vascular changes and plaque instability [ 24, 25].