Sentence examples for mediated by multifunctional from inspiring English sources

Later, cell adhesion is mediated by multifunctional cellular structures consisting of a complex network of transplasma membrane integrins and cytoplasmic proteins linking the extracellular matrix (ECM) to the cytoskeleton, and such adhesion is termed focal adhesion [ 19].

The broad spectrum of activities mediated by these multifunctional HDPs has fueled synthetic peptide design studies intended to increase peptide activity while decreasing toxicity to potentiate the future clinical and commercial applications.

It is well known that after stimulation by ligand, the GPCRs undergo desensitization and internalization mediated by the multifunctional adaptor proteins called arrestins.

Whether AtABCG16 is implicated in the transport of such diverse substrates as ABA and components of the pollen wall or whether the different phenotypes observed are mediated by one multifunctional substrate has to be addressed in the future.

It has been shown earlier that doxorubicin mediated cell cycle arrest can occur either at G0/G1 or G2 check points and is thought to be mediated by the multifunctional transcription factor p53 [ 18].

The raise in Snail levels that we observed in autophagy-deficient hepatocytes was due to a decreased Snail degradation mediated by p62, a multifunctional protein implicated in several signal transduction pathways and in regulating selective autophagy.

These experiments indicate that Na+/H+ exchange activity of proteoliposomes reconstituted with proteins from renal brush-border membranes are inhibited by protein phosphorylation mediated by calcium-calmodulin-dependent multifunctional protein kinase II and stimulated by that mediated by calcium-calmodulin-dependent protein kinase.

Studies were performed to determine the effect of protein phosphorylation mediated by calcium-calmodulin-dependent multifunctional protein kinase II and calcium-phospholipid-dependent protein kinase on Na+/H+ exchange activity.

While previous work has demonstrated that β2ARs can engage distinct signaling and functional cascades mediated by either G proteins or the multifunctional adaptor protein, β-arrestin, the precise role of β-arrestin in skeletal muscle physiology is not known.

We show that adjustments in PIN auxin transport protein levels are mediated by a plant ortholog of the multifunctional Elongator complex.

The hypoxia-induced neovascularization was found to be mediated by interleukin 8 (IL-8), a multifunctional cytokine that shows potent angiogenic activities in vitro and in vivo (Bar-Eli, 1999), and possibly by vascular endothelial growth factor (VEGF), a strong specific mitogen for endothelial cells that also stimulates endothelial cell migration and reorganization (Ferrara and Davis-Smyth, 1997).