Sentence examples for mediated by it from inspiring English sources

Since there are no prior reports of significant and coordinated perturbations of fatty acid and cholesterol biosynthetic pathways with IGF-1 in muscle cells, these findings provide a substantive expansion of our understanding of IGF-1 action and the signal transduction pathways mediated by it, its variants and insulin.

According to OntoUML, "Mediation" is a type of relationship that binds the "Relator" to the elements whose relationship is mediated by it.

The NK1 receptor that SP acted on in BMSCs and the proliferation mediated by it was revealed and confirmed previously.

Since the RAW 264.7 macrophages also express the scavenger receptor A, entry of the adenovirus might be mediated by it.

We had previously shown that the bLZip domain-containing transcription factor, Zhangfei/CREBZF inhibits the growth and the unfolded protein response (UPR) in cells of the D 17 canine osteosarcoma (OS) line and that the effects of Zhangfei are mediated by it stabilizing the tumour suppressor protein p53.

While sexual difference is mediated by representation, it cannot be fully contained within its terms.

Although the reduction of oxidized PTEN appears to be dominantly mediated by Trx, it has been reported that Trx1 inhibits its phosphatase activity by binding in a redox dependent manner to PTEN through disulfide bond formation [45].

As the major catalytic peptidyltransferase activity of the ribosome is mediated by RNA, it is postulated that this complex has its origins within the RNA world, evolving from ribozymes with peptide ligase/RNA replicase functions [2] [4].

To understand the transcriptional regulation mechanisms mediated by RNAPII, it was necessary to evaluate mRNA expression as accurately and quantitatively as possible.

Although many cellular effects of oxidized phospholipids are mediated by receptors it is unlikely that specific receptor binding is the only primary event responsible for lipid activity.

Although data from these complementary experiments provide evidence that genistein regulation of eNOS is mediated by CREB, it should be noted that near depletion of CREB only reduced basal eNOS expression and NO production by less than 50%.