Namely they produce autoantibodies that can cause renal damage via disruption of cellular functions, cytotoxicity mediated by interactions with complement and release of inflammatory mediators.
The repressing effect of Groucho is mediated by interactions with Histone Deacetylases (HDAC, Chen 1999).
Gehne, N. et al. Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops.
So, many motor, cognitive and emotional actions are mediated by interactions among the components of this frontostriatal system.
Development of the trophoblast lineage is mediated by interactions between genetic and epigenetic factors.
The equivalence of the effect on both ligands suggests that this mutation acts independently of ligand type or is mediated by interactions conserved between the two molecules.
RNA folding and binding reactions are mediated by interactions with ions that make up the surrounding aqueous electrolytic milieu.
Of particular importance was to analyze whether the effect of galanin on 5-HT release is mediated by interactions with somatodendritic 5-HT1A receptors or with 5-HT1A receptors at the postsynaptic level.
This indicates that a significant part of the perturbing properties of SP-C in phospholipid bilayers is mediated by interactions of the N-terminal segment.
The effects of leptin hormone are mediated by interactions with several physiological regulatory systems and the cytokine network, and by targeting cells directly.
This transient binding results in further leukocyte activation and subsequent firm adhesion and transendothelial migration of leukocytes, both of which are mediated by interactions between members of the integrin and immunoglobulin superfamily of CAM.
