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All of these effects are thought to be mediated by increased activation of serotonin receptors throughout the brain regions involved.
Enhanced TLR4 reactivity following injury is mediated by increased p38 activation.
Both groups found that NITC is mediated by increased transcription of genes that are ancestrally related to the mutant gene.
Furthermore, these anti-anhedonic effects appeared to be mediated by increased glucose metabolism in the dACC and putamen.
This accumulated hydraulic deterioration is largely mediated by increased vulnerability to cavitation, a process known as cavitation fatigue.
TNF-α increased caspase-3 expression, which was mediated by increased caspase-12 expression.
Telomere elongation is found to repress TERRA expression, which is mediated by increased trimethylation of telomeric H3K9 and by heterochromatic protein HP1α.
In line with this finding, patients with obstructive sleep apnoea are at increased risk of developing T2DM, which could be mediated by increased food intake and/or decreased physical activity159,160, among other mechanisms, owing to disturbed sleep161.
The present study indicates that colchicine induced neuroinflammation may cause systemic inflammation and alteration of immune responses which are mediated by increased cox- 2 activity.
The present study was designed to investigate whether DOI-induced renal vasodilation might be mediated by increased nitric oxide (NO) release/production in renal tissue.
The findings suggest that OT leads to a decrease of control over automatic imitative behaviour mediated by increased self-other merging.
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