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Delayed circadian rhythm phase is also common among individuals with traditionally diagnosed ADHD, and exposure to bright light may be protective against ADHD, a process potentially mediated by improved circadian timing.
Whether this relationship is, for example, mediated by improved psychological well-being or neighbourhood qualities is worthy of further examination.
We examined whether the improvement in parent reported total symptom scores for the intervention group at three and six months, compared with the control group, was mediated by improved sleep (children's sleep habits questionnaire total score) using causal mediation models.
The beneficial health effects of key immunonutrients are mediated by improved cell functions in different splanchnic tissues.
The beneficial effect of creatine may be partially mediated by improved function of the glutamate transporter, which has a high demand for energy and is susceptible to oxidative stress.
Decreased fibrotic evolution by WT-MSCs was likely mediated by improved fibrinolysis (b) in the lungs over the days following acid aspiration acute lung injury (ANOVA p < 0.01 [B]; *Dunnett's post hoc p < 0.05 vs. PBS. PBS n = 5; WT-MSCs n = 5; PTX3−/−-MSCs n = 6) (PBS = acid aspiration acute lung injury + intraperitoneal (i.p).
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Although medication and surgery can control seizures in some patients, the impact of the disease may be mediated by improving psychosocial variables (e.g. social support, locus of control, self-efficacy).
A mechanistic exploration using in vitro and in vivo experiments showed that the neuroprotection of these compounds was at least partly mediated by improving the levels of glutathione (GSH), superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) protein.
The astrocyte-specific anti-inflammatory effect of 2B3-201 raises the possibility that the positive effects of the drug may be mediated by improving astrocyte function.
These effects were mediated by improving the production and function of CD25+FOXP3+ regulatory T cells, whose function is defective in RA patients [ 34].
The indirect effect is mediated by improving urban ventilation which in turn increases the dispersal of the pollutants (Givoni 1991) and also by decreasing ambient temperature, which in turn decelerates the smog formation (Akbari 2002).
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