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Both T2DM and CAD are characterized by chronic, low grade non-specific inflammation, which has long been associated with sterile innate immune responses mediated by heightened levels of serum pro-inflammatory cytokines (TNF-a, IL-6 and IL-1b) [ 16].
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Furthermore, potassium appears to have an antihypertensive effect mediated by increased natriuresis, vasodilation, heightened baroreflex sensitivity, and reduced cardiac sensitivity to catecholamines and angiotensin II [ 57].
Effects on walking speed were mediated by alterations in the cortisol:DHEAS ratio which was heightened among the depressed group.
According to this model, the relationship between traumatic events and the heightened risk for an alcohol use disorders is mediated by the occurrence of PTSD or other posttraumatic psychiatric disorders (Jacobsen et al. 2001; Khantzian 1999).
Our transcriptional analysis of hepatic tissue suggests that the heightened hepatic glucose production capability of GHR-KO mice is mediated by numerous gluconeogenic proteins; further, we only detected evidence for G6PC and PCX being involved in the RIP::IGF-1 transgene's ability to blunt this enhanced gluconeogenic performance.
If the heightened Th2 and Th9 responses caused by Cbl-b deficiency are mediated by Stat6, one would predict that loss of Stat6 should abrogate these hyperresponses in Cblb−/− mice.
Heightened expression of MICA on HCE was found to promote the cytotoxicity mediated by NK cells or CD8+T cells, which could be blocked by an anti-MICA antibody.
Heightened SNS arousal also triggers withdrawal of social safety engagement responses mediated by the parasympathetic nervous system ventral vagal complex (PNS-VVC).
Maternal p110δ inactivation affected the outcome of pregnancy through two pathways: one mediated by poor uNK function leading to reduced arterial remodeling and fetal growth restriction and one characterized by a heightened inflammatory uterine milieu underpinning increased fetal mortality.
It wasn't mediated by television".
"And newspapers are mediated by editors.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com