Sentence examples for mediated by functionally from inspiring English sources

Second, functional redundancy can be mediated by functionally equivalent but heterogeneous components (known as heterogeneous redundancy).

Tsitoura, D.C., DeKruyff, R.H., Lamb, J.R. & Umetsu, D.T. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells.

Although the elimination of CMV infected cells is directly mediated by functionally active CMV specific CD8 T cells [6] [8], the need for CMV specific CD4 T-cell help to maintain or even promote the generation of virus-specific CD8 T cells has clearly been demonstrated in observational studies [9] and interventional trials of adoptive T-cell transfer in stem cell transplant recipients [10] [13].

Briefly, as implied from its name, the CU system transports its protein cargo, known as pilus subunits, across periplasm and outer membrane in a relay manner mediated by two functionally conserved proteins known as a periplasmic chaperone and an outer membrane usher.

This repression takes place in the somatic follicle cells of the ovary and, therefore, is mediated by a functionally different piRNA pathway (Desset et al. 2008; Malone et al. 2009; Pelisson et al. 2002).

The actions of progesterone are mediated by two functionally distinct receptor isoforms, PR-A and PR-B, which are expressed from a single gene as a result of transcription from two alternative promoters [ 8].

It has been suggested that the association between B*57 or B*27 alleles and lower viral loads is mediated by targeting functionally critical and, therefore, more highly conserved parts of the proteome (Allen et al., 2005, Brockman et al., 2007, Crawford et al., 2007, Friedrich et al., 2004, Goulder et al., 1997, Leslie et al., 2004, Liu et al., 2013, Peyerl et al., 2004).

Thus associations are likely to be mediated by the genes functionally related to the phenotypes.

In contrast, if saccade preparation and attentional covert orienting are mediated by anatomically and functionally distinct control processes, these processes might have different effects on the processing of subsequently presented visual events.

The psychopharmacologic effects of nicotine are mediated primarily by functionally diverse neuronal nicotinic acetylcholine receptors (nAChRs), a family of ligand-gated ion channels widely distributed in the brain [9], [10], [11].

Whether these latter effects are mediated by alternative protein receptors functionally coupled to cholesterol, or by cholesterol itself through a protein-independent mechanism, remains to be established.