Sentence examples for mediated by excessive from inspiring English sources

The results suggest that the U. pumila extract and the isolated compound icariside E4 effectively inhibited the NO production and may be useful in preventing inflammatory diseases mediated by excessive production of NO.

These findings clearly reveal that both AD and the MPD are mediated by excessive TSLP levels.

This suggests that the mechanism of glutamate and QUIN gliotoxicity is at least partially mediated by excessive stimulation of NMDARs.

It is known that cellular senescence induced by oncogenic Ras is mainly mediated by excessive signalling through the ERK signalling pathway[19], [20], [21].

We demonstrate that OPT-induced cancer cell death is mediated by excessive endoplasmic reticulum (ER) stress.

We considered how it might be possible to protect organelles against stresses mediated by excessive nutrient conditions.

Endotoxic shock is mediated by an excessive production of proinflammatory cytokines such as TNF-α, IL-1β, IL-6, IL-12 and IFN-γ[13] [15 IFN-γ[13] [15

The present study shows that the cytotoxic effect and induction of apoptosis by Fe-SP is predominantly mediated by the excessive generation of ROS in cell lines derived from NB or OC.

44 Angioedema attacks caused by C1-INH deficiency are mediated by the excessive release of vasoactive bradykinin.

Over again, the activation of p38 MAPK mediated by an excessive ROS generation has been aimed as responsible for the EPCs impaired proangiogenic potential in vivo by limiting cells proliferation and differentiation [ 69].

For instance, in murine Chagas' disease model, the thymus is affected by severe thymocyte depletion mediated by corticosterone and excessive production of TNF- α associated with the export of immature CD4+CD8+ double-positive (DP) cells to the periphery [ 37].