Sentence examples for mediated by elevated from inspiring English sources

Prevailing theories for insulin resistance focus on lipid-mediated mechanisms but also include insulin resistance mediated by elevated concentrations of amino acids and inflammatory signaling molecules as well as combinations of these (2).

The current study initially verified that the effectiveness of Gln as a GLP-1 secretagogue is observed in primary colonic cultures as well as GLUTag cells, and subsequently demonstrated that this is attributable to the activation of both a triggering pathway that elevates intracellular calcium (Cai2+), and an amplifying pathway mediated by elevated cAMP.

The effect of nephropathy on diabetic retinopathy (8, 9) could potentially be mediated by elevated dimethylarginines because all three analytes are renally cleared and ADMA and SDMA are elevated by reduced renal clearance (7, 10).

The presence of CD4 and CD8 cells at the transplant site (Fig. S4) confirms that T cells are present and suggests a degree of T cell response from the host, possibly mediated by elevated CD8-positve cells.

We suggest the enhanced disease severity is caused by a combination of an increase availability of susceptible cell types, dysregulation of immune signaling, and, potentially, enhanced spread of WNV due to destabilization of tissue integrity mediated by elevated inflammation.

The promotion of the angiogenic phenotype in these lesions is supposed to be mediated by elevated levels of pro-inflammatory and pro-angiogenic secretions (cytokines, chemokines and growth factors) from the KS spindle cells [1].

The later phase (3 4 h) is characterized by the elevated level of prostaglandins mediated by the elevated release of leukotrienes and bradykinin.

It is possible that deletion of thymocytes in vivo, in the absence of Bim, is mediated by the elevated Nur77 levels.

The poorer functioning seemed to be, at least in part, mediated by the elevated mood.

It is clear that mammospheres possess efficient base excision repair/SSBR, probably mediated by an elevated level of APE1.

Previous investigations have suggested the special regulation of CKIs under TGFβ1, mediated by an elevated level of c-Myc [ 45- 47].