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Ubiquitin pathway genes tend to be upregulated in cancer mediated by diverse mechanisms.
While a single broadly neutralizing antibody targeting one epitope can mediate neutralization breadth, the findings presented here suggest that a cooperative polyclonal process mediated by diverse antibodies with more limited breadth targeting multiple epitopes also can achieve neutralization breadth against HIV-1.
GABAergic inhibition is crucial in all aspects of neural circuit operation in the cortex and is mediated by diverse interneuron cell types.
This might be mediated by diverse GTPase activity, since the isoform differences predominate near the predicted GTP-binding site.
As described in the previous section, translocation of proteins through the IM can be mediated by diverse SSs.
Therefore, this common in vitro ability of F-BARs to tubulate membranes using a scaffolding mechanism can be mediated by diverse F-BAR-to-F-BAR interactions.
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Solute transport by these pathways is mediated by a diverse, and complex array of transport and secretory processes that are regulated by hormonal, developmental, and physiological factors.
Regulation is mediated by a diverse set of RNA binding regulators, including proteins and RNAs, which interact with specific mRNA sequences that are often found in untranslated regions.
Normal developmental processes of metazoans depend upon cell-cell communication, which is mediated by a diverse yet highly conserved set of secreted protein factors.
IQGAP1 is a scaffold protein and participates in signaling cascades mediated by a diverse group of cell surface receptors [33], including VEGFR-2 [26].
In Geobacter, the electron transfer to the environment was shown to be mediated by a diverse group of c-type cytochromes and possibly involved electrically-conductive microbial nanowires [17] [19].
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