Sentence examples for mediated by cyclin from inspiring English sources

Finally, we demonstrate that miR-21-regulated renal cancer cell proliferation is mediated by cyclin D1 and CDK4.

Networks of rice genes associated with stress response, seed development and cell cycle mediated by cyclin were built from the results generated from yeast two hybrids (Cooper et al., 2003a,b).

To confirm whether the elevated proliferation, based on Ki67 staining, seen in the organ culture might be partly mediated by cyclin B2, we performed TaqMan RT-PCR analysis of these cultures.

Phosphorylation of RB1 protein is mediated by cyclin D/Cdk4/6 and cyclin C/Cdk3 complexes.

They demonstrated that mitochondrial fission, mediated by cyclin B1/Cdk1 phosphorylation of Drp1 at Ser, is required for the hyperproliferation of PASMCs.

54, 55 In another in vitro study, rapamycin inhibited cell proliferation and induced cell cycle arrest in G0/G1 phase mediated by cyclin D3 and p27 deregulation.

The transition from G1 to S phase is regulated by phosphorylation of the retinoblastoma protein (pRB) that is mediated by cyclin-dependent kinases (reviewed in Kaelin, 1999).

Phosphorylation of pRB is mediated by cyclin-dependent kinases which are regulated by cyclins, namely by the Cdk4/cyclin D1 complex and the Cdk2/cyclin E complex.

The inactivation of SIRT2 through inhibitory phosphorylation at Ser is mediated by cyclin-dependent kinases (CDK), CDK1, 2 and 5. HDAC1, 3 and 6 are implicated in the enhancement of AKT signaling through their specific interactions with protein phosphatase 1 (PP1) and AKT.

Inactivation of retinoblastoma family proteins, mediated by both cyclin D and cyclin E, might be the common denominator [ 1].

Progression from the G2 phase to mitosis is mediated by the cyclin-dependent kinase 1 (cyclincyclin B complex.