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Thus it appears that the depolarization is mediated by contributors other than respiration interference.
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Another hub in the network, TGFBR I has been recognized as one of the major contributors to diabetic nephropathy mediated by the TGFB-signalling pathway [83].
Furthermore, OATP1B3 transported six other β-lactam antibiotics, and their uptake clearances by OATP1B3 correlated well with those mediated by rat Oatp1a4, which is the predominant contributor to basolateral uptake of nafcillin by rat hepatocytes.
The heat shock response, mediated by HSF1, appears to be a major contributor to survival during such types of stress.
Their suggestions are mediated by Mr Lessig and a core group of contributors.
The regulatory mechanisms operating in the periphery of the system are mediated by subsets of regulatory cells, now considered principal contributors to peripheral tolerance.
Elevated EREG plasma protein levels, however, were detected in a minor fraction of our breast cancer patient data set, suggesting that EREG is not a primary contributor to breast cancer progression mediated by monocytes in humans.
Taking all these factors together, there is good evidence that more advanced stage of breast cancer at diagnosis will have been a major contributor to avoidable deaths, partly mediated by lower proportions of patients presenting with operable disease.
Compounds inhibiting Cox-2 are of special interest for antiangiogenic therapy because prostaglandins mediated by Cox-2 have been shown to be important contributors to VEGF dependent tumor angiogenesis [ 27].
Infection mediated by medical devices is thought to be a major contributor to hospital-acquired infections [ 1].
Inflammation is considered a prerequisite and important co-contributor to fibrosis and is, in part, mediated by tumor necrosis factor (TNF -α-converting enzyme (TNF -α-converting
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