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Enhancement is mediated by clusters of epitopes on the S protein (33, 34).
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Therefore, ADCC responses mediated by cluster A antibodies in HIV-positive sera involve a sequential opening of the Env trimer on the surface of HIV-1-infected cells.
Few discoveries transform a discipline overnight, but biologists today can manipulate cells in ways never possible before, thanks to a peculiar form of prokaryotic adaptive immunity mediated by clustered regularly interspaced short palindromic repeats (CRISPR).
We describe a new serine protease inhibition motif in which binding is mediated by a cluster of very short hydrogen bonds (<2.3 Å) at the active site.
Together, the results are consistent with a functional link between EGFR activation and neuroglian stabilization, possibly mediated by their clustering in GSL-rich membrane subdomains.
As shown in Figure 4E, the elongation rates mediated by VASP clustered on beads increased in order of their affinities for actin monomers.
Intimin-Tir interaction induces polymerization of F-actin underneath the bound bacterium mediated by the clustering of phosphorylated cytoplasmic domains of Tir that recruit Nck and other cellular proteins.
Our work using a subtropical wild population of N. crassa (Ellison et al. 2011; Palma-Guerrero et al. 2013) further supports that natural variation to drug tolerance occurs and seems to be mediated by zinc cluster transcription factors.
The link between expression responses to changing copper and sulfur amino acid metabolism, which may be mediated by iron sulfur cluster proteins at both extremes, may reflect a broader genomic coupling of copper and iron homeostasis.
Thus, a geomagnetic compass sense due to swimming-induced motion may be mediated by different ampullary clusters or cluster subgroups among taxa.
Hence, analog inputs produce analog outputs, mediated by digital Ras clusters.
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