Sentence examples for mediated by channels from inspiring English sources

To investigate the relevance to endogenous TRPC5 channels, we measured a Ca2+-influx signal evoked by an oxidized phospholipid (PGPC), which we have previously shown is mediated by channels containing TRPC5 and TRPC1 subunits (Al-Shawaf et al., 2010).

The transcellular route crosses the apical and basal cell membranes and is primarily mediated by channels, carriers, pumps, and vesicles.

Furthermore, the SMD of the vascular smooth muscle cell membrane appears to be mediated by channels sensitive to NFA, NPPB, and DIDS.

In plant cells, primary active transport mediated by H+-ATPases and secondary transport mediated by channels and cotransporters are crucial to maintain characteristically high concentrations of K+ and low concentrations of Na+ in cytosol.

A possible scenario is that the PSY-induced raft disruption can also change the overall membrane Ca2+ permeability and/or determine an active Ca2+ influx mediated by channels anchored to lipid rafts.

These results therefore confirm the expression of calcium-activated potassium channels by microglia but also indicate that the current mediated by these channels is not up-regulated after SE.

Our results demonstrate the ability of two pyrazole derivatives to discriminate between the classical Orai-mediated, highly Ca2+ selective signalling pathway and the phospholipase C-dependent Ca2+ entry-mediated by TRPC channels, specifically by TRPC3.

This current, resistant to an Ih specific blocker (see below), is similar to that mediated by T type Ca2+ channels observed in bipolar cells of the rat [21], [33], [34] and shown to participate in synaptic transmission to amacrine cells [35], [36].

These properties are similar to those observed in pig and rat ventricular myocytes [ 18], suggesting that the current is likely mediated by TRPM7-like channels in human atrial myocytes.

Further, we also stimulated the preparation with 50 mM KCl. Presynaptic taste cells respond to depolarization with an influx of Ca2+, mediated by voltage-gated Ca channels [18], [25].

By combining voltage and calcium imaging, we show that calcium signals, elicited by parallel fiber stimulation and mediated by voltage-gated calcium channels, increase non-linearly during high-frequency bursts of electrically constant calcium spikes, because they locally and transiently saturate the endogenous buffer.