A limitation of the study design is the focus on clinician beliefs and attitudes, rather than the social and moral context of the consultation, or the ways in which clinical encounters are mediated by broader social and cultural discourses surrounding obesity.
Transport of amino acids across an epithelium is a complex process mediated by a broad array of amino acid transporters expressed in the plasma membrane (1, 2).
E. coli pathogenesis is mediated by a broad spectrum of virulence factors specific to enteric/gastrointestinal/diarrhoeal pathogens (enterotoxins) or to extraintestinal E. coli (ExPEC) pathogens [ 14– 17].
This residual effect may be mediated by the broad and diffuse nor-adrenergic projections from the locus ceruleus to the rest of the brain (Vogt et al., 2008).
Ducatez et al. found that dietary generalism, and not habitat generalism, is correlated with relative brain size [ 68] suggesting that a relationship between brain size and urban invasion could be mediated by a broad diet.
Interestingly, this dual resistance phenotype is reminiscent of the type of response mediated by the broad spectrum PM resistance gene RPW8.2 from Arabidopsis which has a unique structure in terms of other known R proteins.
Thus, whereas perforant path integrity specifically relates to mnemonic discrimination, mnemonic discrimination may be mediated by a broader MTL network.
Variations in gene expression, mediated by epigenetic mechanisms, may cause broad phenotypic effects in animals.
There is growing experimental evidence in mammals that paternal transmission can be mediated by epigenetic inheritance in its broad sense, through sperm DNA methylation changes (Dias and Ressler, 2014) or altered sperm noncoding RNAs (Gapp et al., 2014).
Expanding on individual reactions to office design changes as specified by social interference theory, we propose that office redesign affects organizational commitment and this relationship is mediated by employee perceptions of the broader work environment.
