Sentence examples for mediated by additional from inspiring English sources
Our novel results suggest this promoter specificity is mediated by additional unknown cis-regulatory elements present in the native promoters that are required for the recruitment of Mam and formation of functional Su(H /NICD/Mam complexes on SPS elements.
In conclusion, while we cannot exclude the possibility that the effect of the two antagonists on c-fos expression could also be mediated by additional targets, a significant effect seems unlikely given the higher specificity of the compounds against the TRPV1 channel and the TRPV1-specific block observed in the CGRP experiments.
Thus the transcriptional regulation by NFIX is mediated by additional mechanisms other than the known NFI-binding sites.
Because no statistical increase in Ac-LDL uptake was observed for CD34+ cells cultured in EC-conditioned medium, the endothelial differentiation of CD34+ cells is mediated by additional factors to the ones secreted by the CD34+-derived ECs.
Since kinase-substrate specificity is often mediated by additional binding events at sites distal to the phosphorylation site, the predictor uses the presence/absence of multiple sequence motifs to evaluate potential substrates.
Some self-interactions also appear to be mediated by additional sites: all the partial fragments of VP19, VP28 and VP51A were shown to interact with their own full length proteins, which implies that the monomers of these proteins might interact via several sites to form the oligomers.
We did not estimate this potential mediation, but our additional analyses indicated that part of the total relationship between education and OWOB may be mediated by wealth (Additional file 8).
Interestingly, transduction studies revealed that while the expression of BTN3A1 alone is sufficient for the activation mediated by 20.1, additional genes located on chromosome 6 are required for PAg-mediated recognition.
Therefore, the cell autonomous effect might be mediated by unidentified additional mechanisms.
However, recent studies imply that ONB effects could be mediated by an additional mechanism.
Instead, it is mediated by an additional Rad52 enzymatic activity that is unique for ssDNA annealing [29, 39, 40].
