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It is believed that behavioral sensitization is mediated by activity of the mesocorticolimbic dopamine system.
Notably, under physiological conditions, this effect could be mediated by activity in a distributed interneuron network, rather than the multiple long stimuli of a single interneuron used in our experiments.The fact that barrage firing occurs exclusively in NPY interneurons is also notable, as NPY has been identified as an endogenous modulator of epileptic activity49.
Graft rejection is usually mediated by activity of T cells, especially cytotoxic T cells.
The latter studies found that the spacing effect was primarily mediated by activity in the inferior frontal gyrus [33], [44].
Although the prevalent view is that blindsight may be mediated by activity in higher cortical areas such as V5/MT [28], [29], [29], it is clear from the data we present here that, visually driven activity in the absence of V1 input also persists in early extrastriate areas V2 and V3, which may therefore contribute to this phenomenon.
In a community sample of people with OA the relationship between physical symptoms (I) and participation restrictions was found to be mediated by activity limitations and depression [ 18].
Similar(48)
These results provide support for an explanation of the effects of parental education as being mediated by activities and practices conducive to development of the child's cognitive and literacy skills (see e.g., Bornstein et al. 1998).
Conversely, the effect of ME could have been entirely mediated by activity-independent mechanisms.
This early process is mediated by activity-dependent mechanisms that occur peripherally at the synaptic level and involve covalent modifications of pre-existing proteins and local protein synthesis [56].
Similar to the ME-induced rearrangement of RGC axons described here, the segregation of RGC axons into ON and OFF sublaminae in the ferret LGN takes place after eye-specific segregation [47], and this segregation is mediated by activity-dependent mechanisms [48], [49].
The maturation of neuronal networks involves translation of sensory experience into synaptic connectivity mediated by activity-dependent gene transcription (20– 20).
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