Neurons undergo long term, activity dependent changes that are mediated by activation of second messenger cascades.
Anti-apoptotic activities of NFκB is generally mediated by activation of set of genes related with cell survival [ 27].
Therefore, in SHRs, consumption of palatable food, compared to regular chow, resulted in increased neuronal activity in the RVLM, which may be mediated by activation of the OX2R.
However, the increase in locomotor activity induced by 8-OH-DPAT, which is mediated by activation of postsynaptic 5-HT1A recepTricklebankletalk et al. 1984), was found to be significantly and dose-dependently blocked by galanin given i.c.v.
In most instances this is mediated by activation of IRF3 and 7 which regulates the IFN-α/β gene expressions.
"... Previous work showed that magnetic electrical field-induced antinoceptive action is mediated by activation of capsaicin-sensitive sensory afferents.
This shift may be mediated by activation of the mineralocorticoid receptor (MR) for cortisol.
We have shown that the inhibitory response is mediated by activation of postsynaptic 5-HT1A receptors.
These experiments suggest that the photodilation is not mediated by activation of neuronal and/or astrocyte Ca2+-dependent neurovascular coupling pathways.
This process involves inhibition of inflammatory signals that are mediated by activation of the transcription factor NF-kB.
The effects of PGI2 are mediated by activation of the cell membrane G-protein-coupled PGI2 receptor (IP receptor).
