Sentence examples for mediated attenuation of from inspiring English sources

The study has been designed to investigate downstream mechanisms in the PTPase inhibition mediated attenuation of diabetes mellitus and hypercholesterolemia-induced vascular endothelial dysfunction.

In the present study, we have delineated an alternative orchestra of signaling events that would also lead to IL1B mediated attenuation of gastrin expression.

Yan et al. reported that miR-n-145 mediated attenuation of activin-induced proliferation of mouse granulosa cells by targeting both activin receptor 1B and cyclin D2 [ 31].

We propose that miRNA mediated attenuation of transcription/translation of tumor suppressors is a necessary step in normal intestinal development allowing for cell proliferation.

Thus, p38 mediated attenuation of SHP-1 activity led to increased basal levels of Lyn phosphorylation, thereby rendering it less sensitive to BCR activation.

Nevertheless, CBD has been hypothesised to reduce anxiety through an anterior cingulate cortex (ACC) mediated attenuation of the amygdala, in response to fearful and angry faces (Fusar-Poli et al., 2009; Kowal et al., 2013).

Functionally, the cytoplasmic domain of TbetaRIII is required to attenuate TGF-beta signaling, whereas TbetaRIII-mediated attenuation of TGF-beta signaling is required for TbetaRIII-mediated inhibition of migration and invasion.

Tonic D2-mediated attenuation of cortical excitation in nucleus accumbens neurons recorded in vitro.

Deng YR, Ma HD, Tsuneyama K, et al. STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.

Our findings support a role for the astrocyte and posttranscriptional regulation in hormonally-mediated attenuation of EAE.

Nonetheless, when considered at the level of DA modulation of interacting systems, our results are consistent in showing a D1-mediated attenuation of amygdaloid and hippocampal afferent inputs to NAc neurons.