Sentence examples for mediated at different from inspiring English sources

This cleavage is mediated at different positions by either α-secretase or β-secretase in different compartments of the cell [ 4].

The control of AR is mediated at different levels, but signalling pathways play a key role by stabilizing or enhancing its transcriptional activity.

The exact mechanisms governing sphingolipid-mediated regulation of autophagy and other cellular processes still remain enigmatic; however, their roles in autophagy appear to be mediated at different stages of the autophagic process.

It is possible that tight spatial and temporal regulation of secretion is achieved by a number of different SNARE complexes interacting and mediating fusion at different rates and/or residing on granules located in different parts of the cell.

Whether these mechanisms function equally in different organs and are globally regulated or mediated at a gene-specific level needs to be further investigated.

Our transcriptome analysis has generated hypotheses about how the transitions to the different modes of energy and carbon metabolism are mediated at the level of gene expression.

Our study is the first to compare methylation status of Th1 and Th2 cytokine genes in children affected by IgE-mediated CMA at different disease stage.

Other studies have shown CCN3 involved in calcium signaling [ 19, 33], associated with Notch signaling [ 17], and able to trigger membrane mediated phosphorylation events [ 34] Some of the cellular effects of CCN3 may also be mediated by different isoforms operating at the level of the nucleus [ 35].

Since inhibition of rejection and receptor downmodulation may, at least partly, be mediated through different types of MHC-Ly49 interactions (cis and trans), our data should not automatically be interpreted as if the threshold effect seen in rejection of hemizygous target cells, like receptor downmodulation, is also due to saturation.

Presumably, the protective effect associated with these mutations is mediated via different mechanisms that converge at the level of Nrf2 activation.

Evidence for distinct pathways of regulation is also reflected in the finding that the overexpression of these proteins is, at least in part, mediated by different transcription factors (see below).