Sentence examples for mediated as it from inspiring English sources

132 Once again, aldosterone-releasing activity of fat cell conditioned medium was not angiotensin II mediated, as it was not inhibited by ARB candesartan.

Looking back, there are some troubling aspects to the movie — its depiction of the Middle East, even mediated as it is through the lenses of history and fable, is regrettable.

Sulphide mineralization within this setting is biogenically mediated as it results from the decay of the soft tissues and leads to the localization of sulphide mineral precipitation on and around these tissues.

However, XIAP downregulation was caspase-mediated as it was blocked by z-VAD.

The specific killing induced by TILs was FasR-mediated, as it was inhibited by ZB4, an antagonistic anti-FasR antibody.

However, Nichols and colleagues [ 30] suggested that the hepatotoxicity of aplaviroc could be idiosyncratic rather than CCR5-mediated, as it was observed in animal models in which aplaviroc does not bind to CCR5.

This enhanced hepatic and splenic uptake was not receptor-mediated as it could not be blocked by coinjection of an excess of unlabelled [Lys]exendin (data not shown).Very low uptake in the liver and spleen was observed when RP-HPLC-purified [Lys(Ga-DOTA)]exendin-3 was injected (0.44 ± 0.05%ID/g and 0.25 ± 0.02%ID/g, respectively).

The emotion of regret is a counterfactually mediated emotion, as it arises due to counterfactual comparison between what is and the more desirable outcome that might have been if a different decision had been made.

Contrary to studies showing that TCS provided little or no estrogenic activity in the estrogen-dependent systems (Foran et al. 2000; Houtman et al. 2004; Ishibashi et al. 2004), we found that TCS exhibited antagonist activity in the ER-mediated bioassay, as it did in the AR-mediated assay (Chen et al. 2007; Tamura et al. 2006).

Human PR-A was not a general repressor of ligand-mediated transcription, as it had no effect on vitamin D receptor function.

The application of antioxidant molecule alone for targeted therapy has limited its application due to bioavailability and stability in biological environment, limitations of which prompted this research of utilizing nanocarrier-mediated delivery, as it could play a pivotal role of being an effective therapeutic agent.