Qian, F. et al. Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T cell proliferation in human epithelial ovarian cancer.
Stein, J. V. et al. The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules.
Interfering with kinetochore activities, including MT binding, triggers a SAC-mediated arrest of mitosis, which frequently leads to cell death [9].
In conclusion, loss of RNase H2 enzyme activity results in p53-mediated arrest of cell growth.
The mechanism of HSCT-mediated arrest of the brain inflammation in X-ALD is currently not clear.
This activation of integrins is due to the phosphorylation of the cytoplasmic domain of both chains of the heterodimeric integrins [ 49, 50], which then leads to an integrin-mediated arrest of the cells on the endothelium [ 51], as will be discussed in detail below.
Furthermore, overexpression of both cyclin D1 and cdk4 clearly blocked FGF-mediated growth arrest of RCS cells, as assayed by FACScan analysis (Fig. 1E), while introduction of either cyclin D1 or cdk4 alone had no significant effect.
Together, these results indicate that both NgR proteins and gangliosides are involved in MAG inhibition, but are not the only molecules to trigger MAG-mediated growth arrest of sensory neurons.
Increased expression of IGF-IR was shown to reduce trastuzumab-mediated growth arrest of HER2-overexpressing breast cancer cells [ 31].
