Sentence examples for mediated alterations in from inspiring English sources

Although the relative contribution of furan mediated alterations in metabolic pathways and antioxidant defense to the overall toxic response to furan, including considerations of dose and time, remains to be established, our work contributes to mapping biological processes and toxicity pathways modulated by reactive electrophiles.

How these individual effects on IS organization are mediated by Nef, whether they represent independent or interconnected activities and how they each contribute to Nef mediated alterations in IS function, however remained unclear.

Our data suggest that transcriptionally mediated alterations in Angpt1, Tek, and Kdr during sepsis may potentially be modulated through targeting histone acetylases/deacetylases.

Src involvement in β3 integrin mediated alterations in TGF-β signaling was assessed by performing Src protein kinase assays, and by interdicting Src function pharmacologically and genetically.

This finding indicates the presence of a modulation of sympathetically mediated alterations in leg vascular conductance within the active muscle during exercise.

Exposure of mouse embryo cell cultures undergoing early neurulation (during the period of gastrulation) demonstrated DNA methylation mediated alterations in gene expression that are proposed to contribute to the FASD phenotype [ 38].

HIV mediated alteration in B cell development and differentiation may result in loss of switched and non-switched memory B cells.

These results indicate that, in microvascular endothelium, Rac1-mediated alterations in contact zone architecture contribute to cAMP-induced barrier stabilization.

These data suggest that iron-mediated alterations in TFAP2 expression levels might influence frataxin mRNA expression during cellular iron deficiency.

Collectively, our results indicate that oncogene-mediated alterations in gene expression play a direct role in metabolic transformation.

Dexamethasone-mediated alterations in the cytoskeleton have been reported previously in EC monolayers (40) and it is known that interfering with microfilaments or microtubules suppresses key angiogenic responses (41).