Sentence examples for mediated alteration of from inspiring English sources

Immune mediated alteration of the terminal sugars of goblet cell mucins in the small intestine of Nippostrongylus brasiliensis-infected rats.

Our results suggest a previously unknown mechanistic basis linking transcriptional dysregulation to cell death in neurodegeneration through TBP mediated alteration of Vdac1 expression.

Such an hαSyn mediated alteration of VMAT/CAT-1 GFP distribution further deVMAT/CAT-1 GFPAT/CAT-1::GFP fluorescence of distributionites was only located in discrete punctate spots without visible lines in L4 worms (further4I–M), which was prior to the obvious start of developedeuron degenerandon in this worm VMAT/CAT-1 GFP

Considering the crucial role of PDGF signaling in pulmonary vascular remodeling [8], [9], the increased presence of growth factors signaling in human and experimental PAH [8], [10], [13] and PDGF and FCS mediated alteration of GSK3ß activity, collectively suggests GSK3ß plays an important role in the pathogenesis of PAH.

We found that the decreased cell proliferation and survival induced by N-cadherin overexpression was abrogated by N-cadherin blockade, which reverses N-cadherin-LRP5 interaction in osteoblasts [39] and was partly restored by Wnt3a, indicating that N-cadherin-LRP5 mediated alteration of canonical Wnt signalling contributes to the negative effect of N-cadherin on cell growth.

Chemically mediated alteration of expression of Stra8 (stimulated by retinoic acid gene 8) differentially affects the timing of meiosis in the ovary and testes and could influence sex.

In some species these changes are long-term, hormonally mediated alterations of coloration and frequently include a proliferation of the carotenoid (red and yellow) pigments.

Here we use a combination of Nef mutagenesis and pharmacological inhibition to analyze the relative contribution of these effects to Nef mediated alterations of IS organization and function on TCR stimulatory surfaces.

A single dose of an unselective beta-blocker abolished the HR differences between these genotypes, thus indicating that the studied differences involve central nervous system mediated alterations of heart rate and blood pressure.

Inflammatory responses are likely to be due to oxidative-stress mediated alterations of cytokine expression including interleukin-6 [ 83].

The mechanisms underlying olig2 regulation could be related to PSA-NCAM mediated alterations of cell proliferation, survival or differentiation [ 19, 41- 48] 48] and remain to be elucidated.