Sentence examples for mediated adaptive immunity from inspiring English sources

We explore the mechanisms that allow the bacteria to avoid detection by innate immune cells via their pattern recognition receptors, to escape T-cell mediated adaptive immunity, and to reprogram the immune system towards tolerance rather than immunity.

T-cell mediated adaptive immunity is considered to play a major role in anti-tumour immunity.

IL-6-deficient mice showed enhanced susceptibility during early infection with Mtb where T-cell mediated adaptive immunity is yet to fully develop [ 146].

In this noncanonical pathway (Fig. 1B), IKKα mediated processing of p100 results in the nuclear translocation of RelB-p52 heterodimers, and plays a key role in B-cell mediated adaptive immunity (Senftleben et al., 2001).

Intervention on T cell mediated adaptive immunity would be, in theory, ideal, given the possibility of focusing the approach on one or more possible antigens involved in the disease process, thus sparing the patient generalized immune suppression.

Removal of ORFs to form HD Ads diminishes longer term humoral and cell mediated adaptive immunity to the vectors and has been useful to prolong transgene expression through [ 46].

Pathogen-associated molecular patterns (PAMPs) and their pattern recognition receptors (PRR), the escape from the T cell-mediated adaptive immunity and reprogramming of the immune system are discussed.

In particular, the close interaction of protein homeostasis with immune response pathways is a largely neglected aspect of how impaired proteostasis within a single cell outreaches its neighborhood: Proteasome function is essential for MHC class I-mediated adaptive immunity against viral and intracellular infections [14].

Lastly, cell-mediated adaptive immunity can be responsible for the elimination of vector transduced cells.

The +IM model uses IFN-α as a surrogate to represent the innate immunity, and considers only the cell-mediated adaptive immunity.

Taken together, these results suggest an early activation of DC functions, indicative of an early capacity to present antigens and activate T cell-mediated adaptive immunity upon Mtb infection.